{"id":3377,"date":"2019-12-11T07:49:06","date_gmt":"2019-12-11T07:49:06","guid":{"rendered":"http:\/\/www.mymedicplus.com\/news\/?p=3377"},"modified":"2021-03-31T00:54:51","modified_gmt":"2021-03-30T19:24:51","slug":"more-women-are-self-treating-endometriosis-with-cannabis-and-cbd-but-is-it-safe","status":"publish","type":"post","link":"https:\/\/www.mymedicplus.com\/blog\/more-women-are-self-treating-endometriosis-with-cannabis-and-cbd-but-is-it-safe\/","title":{"rendered":"More Women are Self-Treating Endometriosis with Cannabis and CBD \u2014 But is it Safe?"},"content":{"rendered":"\n<p>Source: florence-health.com<\/p>\n<p>For the\u00a0estimated\u00a011 percent of American women between1 5 and 44 living with endometriosis,\u00a0symptoms\u00a0like severe pain, fatigue, and nausea can profoundly disrupt their lives. Yet\u00a0endometriosis remains\u00a0under-diagnosed, with a lack of effective treatments.<\/p>\n<p>That\u2019s why many women are taking symptom relief into their own hands by using\u00a0cannabis, according to a recent\u00a0survey\u00a0published this November in the\u00a0Journal of Obstetrics and Gynaecology Canada.\u00a0Other women are turning to\u00a0cannabidiol (CBD)\u00a0for pain relief, hoping to address the symptoms without the high.\u00a0<\/p>\n<p>\u201cPain relief in endometriosis is an important topic, as it can impact women on so many levels, including work, relationships, academic studies, and of course their mental health,\u201d says study co-author\u00a0Mike Armour, PhD, a post-doctoral research fellow in women\u2019s health at Western Sydney University\u2019s NICM Health Research Institute, a government-funded group that focuses on integrative and complementary medicine research and policy in Australia.<\/p>\n<p>Dr. Armour\u2019s team surveyed nearly 500 Australian women between the ages of 17 and 45 and found that 13 percent say they use cannabis to self-treat endometriosis symptoms. The authors estimate that their findings suggest approximately 10 percent of Australian women with endometriosis use cannabis for symptom and pain management.<\/p>\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_82_2 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Table of Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/www.mymedicplus.com\/blog\/more-women-are-self-treating-endometriosis-with-cannabis-and-cbd-but-is-it-safe\/#Why_are_patients_self-managing_their_symptoms\" >Why are patients self-managing their symptoms?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/www.mymedicplus.com\/blog\/more-women-are-self-treating-endometriosis-with-cannabis-and-cbd-but-is-it-safe\/#The_difference_between_cannabis_and_CBD\" >The difference between cannabis and CBD<\/a><ul class='ez-toc-list-level-4' ><li class='ez-toc-heading-level-4'><ul class='ez-toc-list-level-4' ><li class='ez-toc-heading-level-4'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/www.mymedicplus.com\/blog\/more-women-are-self-treating-endometriosis-with-cannabis-and-cbd-but-is-it-safe\/#How_can_cannabis_and_CBD_affect_endometriosis\" >How can cannabis and CBD affect endometriosis?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-4'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/www.mymedicplus.com\/blog\/more-women-are-self-treating-endometriosis-with-cannabis-and-cbd-but-is-it-safe\/#What_the_research_says\" >What the research says<\/a><\/li><\/ul><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/www.mymedicplus.com\/blog\/more-women-are-self-treating-endometriosis-with-cannabis-and-cbd-but-is-it-safe\/#What_should_you_tell_patients_with_endometriosis_about_using_CBD_or_cannabis\" >What should you tell patients with endometriosis about using CBD or cannabis?\u00a0<\/a><ul class='ez-toc-list-level-4' ><li class='ez-toc-heading-level-4'><ul class='ez-toc-list-level-4' ><li class='ez-toc-heading-level-4'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/www.mymedicplus.com\/blog\/more-women-are-self-treating-endometriosis-with-cannabis-and-cbd-but-is-it-safe\/#Understanding_the_risks\" >Understanding the risks<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-4'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/www.mymedicplus.com\/blog\/more-women-are-self-treating-endometriosis-with-cannabis-and-cbd-but-is-it-safe\/#Safer_alternatives\" >Safer alternatives<\/a><\/li><\/ul><\/li><\/ul><\/li><\/ul><\/nav><\/div>\n<h2><span class=\"ez-toc-section\" id=\"Why_are_patients_self-managing_their_symptoms\"><\/span>Why are patients self-managing their symptoms?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Women frequently report\u00a0that they can\u2019t get endometriosis symptoms under control with recommended medications or surgery; there\u2019s little evidence to show current treatments relieve endometriosis pain. NSAIDS like ibuprofen, for one,\u00a0don\u2019t appear to be\u00a0effective, and there\u2019s\u00a0a strong potential\u00a0for addiction and abuse with opioid painkillers. Although research suggests hormonal birth control\u00a0can\u00a0reduce symptoms, many women\u00a0stop or avoid using it\u00a0due to perceived side effects like mood swings and depression.\u00a0<\/p>\n<p>\u201cWomen with endometriosis often report that despite various medications, they have pain that is difficult to deal with,\u201d Dr. Armour tells Florence Health. That\u2019s why it\u2019s not surprising they\u2019re turning to cannabis and CBD, he adds, since limited studies suggest these drugs\u00a0may\u00a0(or may not) relieve pain.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"The_difference_between_cannabis_and_CBD\"><\/span>The difference between cannabis and CBD<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Cannabis is\u00a0the most popular\u00a0illicit drug in the United States;\u00a0there has been a steady rise in\u00a0use every year since 2007, with\u00a07.7 percent of American adults\u00a0reporting using it within the past month as of 2017. That may be in part because it\u2019s well on its way to becoming a legal medical therapy. A total of 33 states and the District of Columbia have legalized\u00a0medical marijuana\u00a0to date; 11 states and D.C.\u00a0also permit\u00a0marijuana for recreational use, with another 16 states having decriminalized the possession of small amounts of the drug.<\/p>\n<p><strong>\u201cPrescribing\u201d CBD and Cannabis<\/strong><\/p>\n<p>Marijuana remains illegal at the federal level, so the act of prescribing it is still illegal, even in states that have legalized it. Physicians and some APPs can, however, write a recommendation for and discuss the benefits of the plant if the patient suffers from a qualifying condition covered by their local law (usually severe conditions like cancer, HIV\/AIDS, glaucoma, or multiple sclerosis).<\/p>\n<p>Because the Drug Enforcement Agency\u00a0classifies cannabis as a schedule 1\u00a0drug \u2014 with more restrictions than even fentanyl or methadone \u2014 officially, there are \u201cno currently accepted medical use and high potential for addiction.\u201d It requires\u00a0a rigorous approval process\u00a0to study, so to-date there\u2019s little peer-reviewed research. That leaves providers hesitant to recommend a drug that\u2019s hasn\u2019t been rigorously studied and whose contents and dosage aren\u2019t regulated by the FDA.<\/p>\n<p>Meanwhile,\u00a0interest in cannabidiol, or CBD, has skyrocketed\u00a0in recent years. While CBD is an essential component of marijuana, it doesn\u2019t contain tetrahydrocannabinol (THC) and therefore doesn\u2019t cause a \u201chigh.\u201d A full 14 percent of American adults say they use CBD, according to\u00a0an August 2019 Gallup poll, most often for pain (40 percent), anxiety (20 percent), and insomnia (11 percent).<\/p>\n<p>Only one CBD-derived drug, which treats seizures in children, has been\u00a0approved by the Food &amp; Drug Administration (FDA). All 50 states have legalized CBD in some form, and retailers have added it to pretty much any product you can imagine \u2014 from cheeseburgers to toothpicks to mouth wash.<\/p>\n<h4><span class=\"ez-toc-section\" id=\"How_can_cannabis_and_CBD_affect_endometriosis\"><\/span><strong>How can cannabis and CBD affect endometriosis?<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h4>\n<p>Cannabis mimics endocannabinoids, natural molecules that act on the endocannabinoid system (ECS), which maintains homeostasis in the body. ECS receptors, in turn, are found throughout the human body. The ECS participates in a wide variety of processes, including pain, stress, sleep, metabolism, immune function and reproduction.\u00a0<\/p>\n<p>While research is lacking, Dr. Armour says there\u2019s another reason to believe cannabis could have a particularly powerful effect on endometriosis pain. Both the uterus and ovaries have highly expressed cannabinoid receptors, he explains. Some researchers\u00a0even think\u00a0cannabis could slow the growth of endometrial tissue.<\/p>\n<p>\u201cThe endocannabinoid system has been found recently to interact with specific mechanisms associated with pain,\u201d explains Dr. Armour. \u201cIt also appears to play an important role in cellular proliferation and apoptosis, which may explain why cannabis is being used by women with endometriosis. However, little has been done clinically to investigate this currently.\u201d<\/p>\n<h4><span class=\"ez-toc-section\" id=\"What_the_research_says\"><\/span><strong>What the research says<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h4>\n<p>While there\u2019s little research into cannabis for pain,\u00a0one recently published paper\u00a0found it may can effectively reduce pelvic pain and opioid use. In Dr. Armour\u2019s study, on average, respondents rated the effectiveness of cannabis a 7.6 out of 10, with 55 percent reporting they were able to reduce the need for pharmaceuticals by at least half. Women reported the greatest improvements in sleep and nausea\/vomiting, with only 10 percent saying they experienced adverse side effects, like anxiety, drowsiness, and rapid heart rate.\u00a0<\/p>\n<p>CBD, meanwhile, appears to have analgesic, anti-inflammatory, and immunomodulatory properties \u2014 but \u201cthe jury is out at the moment as to whether it can provide as much potential pain relief in endometriosis as THC does,\u201d says Dr. Armour.\u00a0<\/p>\n<h2><span class=\"ez-toc-section\" id=\"What_should_you_tell_patients_with_endometriosis_about_using_CBD_or_cannabis\"><\/span>What should you tell patients with endometriosis about using CBD or cannabis?\u00a0<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>For now,\u00a0researchers agree\u00a0that there\u2019s not enough research to make a conclusion about the benefits or risks of cannabis. People who are at risk of developing addiction or schizophrenia should avoid it altogether, while patients with lung disease should avoid smoking it since it causes airway inflammation, wheezing and chest tightness.<\/p>\n<h4><span class=\"ez-toc-section\" id=\"Understanding_the_risks\"><\/span><strong>Understanding the risks<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h4>\n<p>For patients interested in using cannabis, \u201ctalking with a physician who understands the ECS and has experience in prescribing cannabis is an important first step,\u201d says Dr. Armour. \u201cLike all medications, it still comes with certain risks.\u201d\u00a0<\/p>\n<p>CBD, on the other hand, may seem less risky to recommend, as it doesn\u2019t have the psychoactive effect of THC and no known risk of abuse or dependence, notes Dr. Armour. But there still are dangers.<\/p>\n<p>Because CBD isn\u2019t regulated by the FDA, it\u2019s impossible to confirm the exact ingredients or concentration in any given supplement. The\u00a0FDA has found\u00a0some CBD products contain contaminants like pesticides and heavy metals.\u00a0<\/p>\n<p>What\u2019s more,\u00a0CBD can raise levels of certain medications. \u201c[It\u2019s] been shown in preclinical and case studies to change the way certain medications are metabolized. It appears to be of more concern than THC in this particular regard,\u201d notes Dr. Armour. Providers should ask patients taking CBD about any other medications they\u2019re on and closely monitor for adverse side effects, he adds.<\/p>\n<h4><span class=\"ez-toc-section\" id=\"Safer_alternatives\"><\/span><strong>Safer alternatives<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h4>\n<p>Dr. Armour also calls out the other, nonpharmacological treatments that can address endometriosis symptoms. Some women find relief from heat packs, hot baths, and hot water bottles.\u00a0Research\u00a0suggests that acupuncture twice a week for several months may reduce pelvic pain, although it\u2019s unclear whether the effect lasts after patients complete treatment. And\u00a0a low-FODMAP diet\u00a0may help improve any IBS-like symptoms. Just remind patients that this eating plan is for short periods of time.<\/p>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":3378,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[2540,389,360,2539,584,113],"class_list":["post-3377","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized","tag-cbd","tag-endometriosis","tag-pain","tag-self-treating","tag-treatments","tag-women"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>More Women are Self-Treating Endometriosis with Cannabis and CBD \u2014 But is it Safe? - MyMedicPlus<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.mymedicplus.com\/blog\/more-women-are-self-treating-endometriosis-with-cannabis-and-cbd-but-is-it-safe\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"More Women are Self-Treating Endometriosis with Cannabis and CBD \u2014 But is it Safe? 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