{"id":6073,"date":"2020-11-04T10:41:54","date_gmt":"2020-11-04T05:11:54","guid":{"rendered":"http:\/\/www.mymedicplus.com\/news\/?p=6073"},"modified":"2022-03-12T14:53:43","modified_gmt":"2022-03-12T09:23:43","slug":"this-is-indeed-real-race-obesity-drive-risk-for-poor-outcomes-death-in-covid-19","status":"publish","type":"post","link":"https:\/\/www.mymedicplus.com\/blog\/this-is-indeed-real-race-obesity-drive-risk-for-poor-outcomes-death-in-covid-19\/","title":{"rendered":"\u2018This is indeed real\u2019: Race, obesity drive risk for poor outcomes, death in COVID-19"},"content":{"rendered":"\n\n\n<p>Source &#8211; https:\/\/www.healio.com\/<\/p>\n<p>Obesity and race are additive, multiplicative mediators or confounders influencing COVID-19 outcomes among American adults, and the disparities have substantial implications for medical and public health responses, according to a speaker.<\/p>\n<p>\u201cDue to the complexity of the relationship between COVID-19, obesity and race\/ethnicity, studies show conflicting results with regard to the reasons behind the greater morbidity and mortality noted in communities of color in the U.S.,\u201d\u00a0<strong>Fatima Cody Stanford, MD, MPH, MPA, FAAP, FACP, FAHA, FTOS,<\/strong>\u00a0an obesity medicine physician scientist at Massachusetts General Hospital and Harvard Medical School, told Healio. \u201cAlmost 8 months into this pandemic, we have learned that there is no clear answer as to why these disparities exist. However, it does appear that better health at baseline lends itself to the best outcomes with COVID-19. We need more studies to ascertain this relationship.\u201d<\/p>\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_81 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Table of Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-4'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/www.mymedicplus.com\/blog\/this-is-indeed-real-race-obesity-drive-risk-for-poor-outcomes-death-in-covid-19\/#Disproportionate_outcomes\" >Disproportionate outcomes<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-4'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/www.mymedicplus.com\/blog\/this-is-indeed-real-race-obesity-drive-risk-for-poor-outcomes-death-in-covid-19\/#A_%E2%80%98complex_relationship\" >A \u2018complex relationship\u2019<\/a><\/li><\/ul><\/nav><\/div>\n<h4><span class=\"ez-toc-section\" id=\"Disproportionate_outcomes\"><\/span>Disproportionate outcomes<span class=\"ez-toc-section-end\"><\/span><\/h4>\n<p>There is still much to be learned about the pathophysiology of COVID-19, but it has become clear that\u00a0Black Americans are disproportionately affected\u00a0by the novel coronavirus and are far more likely to experience its more severe outcomes, including ICU admission, mechanical ventilation and death, Stanford said during an online presentation at ObesityWeek Interactive.<\/p>\n<p>\u201cWhen we look at the pandemic\u2019s racial disparity &#8230; COVID-19 deaths per 100,000 people, we can see that Black Americans share a large burden,\u201d Stanford said during the presentation. \u201cI can tell you, talking to my parents who lost ten of their friends to this pandemic, my best friend who lost her father, and my mentee who is an internal medicine physician and has lost both parents, that this is indeed real.\u201d<\/p>\n<p>In a study published in June in\u00a0<em>The New England Journal of Medicine,\u00a0<\/em>researchers showed that among 3,481 patients with COVID-19, Black adults were nearly twice as likely to be hospitalized as their white counterparts, with an OR of 1.96 after adjustments for multiple variables (95% CI, 1.62-2.37). Obesity, as well as residence in a low-income area, were also associated with increased odds for hospital admission in the study, Stanford said.<\/p>\n<p>In another analysis published in\u00a0<em>Clinical Infectious Diseases\u00a0<\/em>in August, researchers demonstrated that Hispanic men and women with COVID-19 were significantly more likely to be admitted to the ICU and require mechanical ventilation compared with Black and white adults, Stanford said.<\/p>\n<h4><span class=\"ez-toc-section\" id=\"A_%E2%80%98complex_relationship\"><\/span>A \u2018complex relationship\u2019<span class=\"ez-toc-section-end\"><\/span><\/h4>\n<p>The\u00a0inflammatory state\u00a0that typically accompanies obesity is associated with several disease processes, including impaired adipogenesis, oxidative stress and insulin resistance, Stanford said. Those processes can lead to metabolic syndrome, type 2 diabetes and cardiovascular disease. Stress \u2014 including post-traumatic stress disorder and depression \u2014 acts through the brain to further affect eating and exercise behaviors, Stanford said.<\/p>\n<p>\u201cIt is important for us to recognize that these are intertwined,\u201d Stanford said.<\/p>\n<p>Adding to the burden, a person\u2019s economic status, underlying health conditions and actual pathophysiological differences in inflammation may lead to the health disparities observed among underrepresented adults, Stanford said.<\/p>\n<p>The additive effects create perfect storm for worse COVID-19 outcomes, she said.<\/p>\n<p>\u201cWe need to be cognizant of the fact the people who are disproportionately impacted are those that have less power to deal with these issues,\u201d Stanford said. \u201cBetter chronic disease management, particularly surrounding obesity, which has borne itself out to be one of the major risk factors for COVID-19, is necessary for the treatment of obesity across the age spectrum, particularly in those communities that look like mine.\u201d<\/p>\n<p>Stanford said the COVID-19 story \u201chas not yet been completely written.\u201d<\/p>\n<p>\u201cThere is still a lot for us to learn as we conduct research that will hopefully go beyond this jump to publish,\u201d Stanford said. \u201cWe can make an impact. We know that issues related to structural racism and related to the history of this country have made it that certain groups are disproportionately impacted by chronic and acute diseases like COVID-19.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":6074,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[43],"tags":[3204,1019,4137,51,4138,83],"class_list":["post-6073","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-weight-loss-gain","tag-covid-19","tag-death","tag-indeed","tag-obesity","tag-outcomes","tag-risk"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.0 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>\u2018This is indeed real\u2019: Race, obesity drive risk for poor outcomes, death in COVID-19 - MyMedicPlus<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.mymedicplus.com\/blog\/this-is-indeed-real-race-obesity-drive-risk-for-poor-outcomes-death-in-covid-19\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u2018This is indeed real\u2019: Race, obesity drive risk for poor outcomes, death in COVID-19 - 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