{"id":6159,"date":"2020-11-07T12:12:02","date_gmt":"2020-11-07T06:42:02","guid":{"rendered":"http:\/\/www.mymedicplus.com\/news\/?p=6159"},"modified":"2022-03-12T14:57:12","modified_gmt":"2022-03-12T09:27:12","slug":"is-it-safe-to-take-melatonin-every-night","status":"publish","type":"post","link":"https:\/\/www.mymedicplus.com\/blog\/is-it-safe-to-take-melatonin-every-night\/","title":{"rendered":"Is It Safe to Take Melatonin Every Night?"},"content":{"rendered":"\n\n\n<p>Source &#8211; https:\/\/www.healthline.com\/<\/p>\n<ul class=\"css-17ztj4b\">\n<li class=\"css-t753mo\">How it works<\/li>\n<li class=\"css-t753mo\">Dosages<\/li>\n<li class=\"css-t753mo\">Risks of nightly doses<\/li>\n<li class=\"css-t753mo\">Side effects<\/li>\n<li class=\"css-t753mo\">Multiple doses<\/li>\n<li class=\"css-t753mo\">Interactions<\/li>\n<li class=\"css-t753mo\">When to seek care<\/li>\n<li class=\"css-t753mo\">Bottom line<\/li>\n<\/ul>\n<div class=\"css-1u22pos\">\n<p>Melatonin\u00a0is a hormone that your body naturally produces. It plays a role in regulating your sleep-wake cycle.<\/p>\n<p>There\u2019s also a lab-made version of melatonin that\u2019s available as an over-the-counter supplement. Some people use\u00a0melatonin supplements\u00a0to help with sleep problems like jet lag and insomnia.<\/p>\n<p>In this article we\u2019ll explore how exactly melatonin works and whether it\u2019s safe to take melatonin supplements every night.<\/p>\n<\/div>\n<div class=\"css-0\">\n<div>How does melatonin work?<\/div>\n<\/div>\n<div>\u00a0<\/div>\n<div>\n<p>Natural melatonin is predominantly made in your\u00a0pineal gland, which is located in your brain. Light exposure inhibits the production of melatonin, but darkness stimulates it.<\/p>\n<p>Melatonin levels in your brain begin to increase at dusk as the sun goes down and darkness falls. They reach their peak levels in the middle of the night and start decreasing as dawn gets closer.<\/p>\n<p>The action of melatonin inhibits signals in your brain that promote wakefulness. This helps encourage sleep by making you feel tired or drowsy as you get closer to bedtime.<\/p>\n<p>Because of melatonin\u2019s sleep-promoting effects, melatonin supplements are used to treat a variety of sleep problems. These can include:<\/p>\n<div id=\"onequarter-of-article\">\n<ul>\n<li>insomnia<\/li>\n<li>jet lag<\/li>\n<li>shift work sleep disorder<\/li>\n<li>delayed sleep-wake phase disorder<\/li>\n<li>sleep problems in children with\u00a0autism\u00a0or\u00a0attention deficit hyperactivity disorder (ADHD)<\/li>\n<\/ul>\n<div><a name=\"dosages\"><\/a>What\u2019s a safe dosage?<\/div>\n<p>The Food and Drug Administration (FDA) doesn\u2019t regulate melatonin as a drug. Because of this, there\u2019s limited information on the optimal, safe dosage of melatonin.<\/p>\n<p>In fact, the doses of melatonin supplements that have been used in various scientific studies vary widely, from\u00a00.1 to 10 milligrams (mg)<span class=\"css-1mdvjzu icon-hl-trusted-source-after\"><span class=\"sro\">Trusted Source<\/span><\/span>. One 2017 review defines a typical dose of melatonin to be between\u00a01 and 5 mg<span class=\"css-1mdvjzu icon-hl-trusted-source-after\"><span class=\"sro\">Trusted Source<\/span><\/span>.<\/p>\n<p>Melatonin typically takes\u00a01 to 2 hours\u00a0to work, so it\u2019s often taken up to 2 hours before bedtime.<\/p>\n<p>If you\u2019re looking to try melatonin for the first time, it may be best to begin with a lower dose. Your doctor can help recommend a safe dose for you to start with.<\/p>\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_84 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Table of Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/www.mymedicplus.com\/blog\/is-it-safe-to-take-melatonin-every-night\/#Melatonin_for_children\" >Melatonin for children<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/www.mymedicplus.com\/blog\/is-it-safe-to-take-melatonin-every-night\/#Melatonin_for_older_adults\" >Melatonin for older adults<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/www.mymedicplus.com\/blog\/is-it-safe-to-take-melatonin-every-night\/#What_to_know_about_dietary_supplements_and_safety\" >What to know about dietary supplements and safety<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/www.mymedicplus.com\/blog\/is-it-safe-to-take-melatonin-every-night\/#What_medications_and_substances_does_melatonin_interact_with\" >What medications and substances does melatonin interact with?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/www.mymedicplus.com\/blog\/is-it-safe-to-take-melatonin-every-night\/#Are_there_any_people_who_should_avoid_taking_melatonin\" >Are there any people who should avoid taking melatonin?<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/www.mymedicplus.com\/blog\/is-it-safe-to-take-melatonin-every-night\/#i\" >\u00a0<\/a><\/li><\/ul><\/nav><\/div>\n<h3><span class=\"ez-toc-section\" id=\"Melatonin_for_children\"><\/span>Melatonin for children<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>Like melatonin for adults, there\u2019s not much information on the optimal, safe dosage\u00a0for children. Dosage may also vary depending on a child\u2019s age. One\u00a02016 review<span class=\"css-1mdvjzu icon-hl-trusted-source-after\"><span class=\"sro\">Trusted Source<\/span><\/span>\u00a0suggests the following age-based dosages 30 to 60 minutes before bedtime:<\/p>\n<ul>\n<li>1 mg for infants<\/li>\n<li>2.5 to 3 mg for older children<\/li>\n<li>5 mg for adolescents<\/li>\n<\/ul>\n<p>Because there aren\u2019t clear dosing guidelines regarding melatonin for children, be sure to speak to your child\u2019s pediatrician before giving melatonin to your child.<\/p>\n<h3><span class=\"ez-toc-section\" id=\"Melatonin_for_older_adults\"><\/span>Melatonin for older adults<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>The amount of melatonin your body produces decreases with age. Because of this, melatonin supplements may be helpful for older adults who are\u00a0having trouble falling asleep.<\/p>\n<p>Researchers are still looking into the optimal melatonin dosage for older adults. One\u00a02016 review\u00a0of sleep aids for older adults suggests a dosage of 1 to 2 mg of immediate-release melatonin 1 hour before bedtime.<\/p>\n<h3><span class=\"ez-toc-section\" id=\"What_to_know_about_dietary_supplements_and_safety\"><\/span>What to know about dietary supplements and safety<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>The FDA classifies melatonin as a dietary supplement, meaning that it\u2019s regulated less strictly than a regular drug. For dietary supplements, label claims and product safety don\u2019t have to meet FDA approval before they\u2019re marketed.<\/p>\n<p>A\u00a02017 study<span class=\"css-1mdvjzu icon-hl-trusted-source-after\"><span class=\"sro\">Trusted Source<\/span><\/span>\u00a0of 31 different melatonin supplements found that the actual melatonin content of 71 percent of the products didn\u2019t match the claim on the label. Additionally, 26 percent of products contained\u00a0serotonin, which can be potentially harmful even in small doses.<\/p>\n<p>When shopping for melatonin supplements, look for products that are \u201cUSP verified.\u201d\u00a0United States Pharmacopeia (USP)\u00a0is an independent organization that works to ensure proper quality and dosing of dietary supplements.<\/p>\n<div><a name=\"risks-of-nightly-doses\"><\/a>Are there any risks involved with taking melatonin every night?<\/div>\n<p>According to the\u00a0National Center for Complementary and Integrative Health (NCCIH), short-term use of melatonin supplements appears to be safe for most adults and children. However, information on the effects of long-term melatonin supplements is limited.<\/p>\n<p>Some studies<span class=\"css-1mdvjzu icon-hl-trusted-source-after\"><span class=\"sro\">Trusted Source<\/span><\/span>\u00a0have indicated that long-term melatonin use in adults may cause mild side effects when compared to a placebo. Studies into the effects of long-term melatonin use in children remains limited.<\/p>\n<p>Because melatonin levels naturally decrease at the beginning of puberty, there\u2019s some concern that long-term melatonin use in children may delay puberty onset. However,\u00a0more research<span class=\"css-1mdvjzu icon-hl-trusted-source-after\"><span class=\"sro\">Trusted Source<\/span><\/span>\u00a0is needed.<\/p>\n<div><a name=\"side-effects\"><\/a>What happens if you take too much melatonin?<\/div>\n<p>Melatonin is generally safe. However, mild\u00a0side effects<span class=\"css-1mdvjzu icon-hl-trusted-source-after\"><span class=\"sro\">Trusted Source<\/span><\/span>\u00a0can sometimes occur, particularly if you take higher doses or extended-release formulations.<\/p>\n<p>The\u00a0side effects\u00a0of melatonin can include:<\/p>\n<ul>\n<li>feeling\u00a0drowsy\u00a0or sleepy<\/li>\n<li>headache<\/li>\n<li>dizziness<\/li>\n<li>nausea<\/li>\n<li>increased urination\u00a0or\u00a0bedwetting\u00a0(children)<\/li>\n<\/ul>\n<p>Some less common side effects of melatonin include:<\/p>\n<ul>\n<li>irritability<\/li>\n<li>abdominal cramps<\/li>\n<li>mild\u00a0tremors<\/li>\n<li>feelings of\u00a0depression\u00a0or anxiety<\/li>\n<li>confusion\u00a0or\u00a0disorientation<\/li>\n<li>low blood pressure (hypotension)<\/li>\n<\/ul>\n<p>If you experience\u00a0side effects from melatonin, stop taking it and speak with your doctor. They may recommend using a lower dose or trying out an alternative medication or\u00a0sleep aid.<\/p>\n<div><a name=\"multiple-doses\"><\/a>Is it safe to take more than one dose during the night?<\/div>\n<p>You may be wondering what happens if you take a dose of melatonin and find that you still can\u2019t fall asleep. Can you take another dose?<\/p>\n<p>While taking an additional dose is\u00a0unlikely to cause harm, it may increase your risk for experiencing unwanted side effects.<\/p>\n<p>If you find that melatonin isn\u2019t helping you fall asleep, stop using it. Your doctor may be able to suggest different medications or strategies to help you fall asleep.<\/p>\n<div class=\"css-1cg0byz\">\n<aside class=\"css-0\">\n<div>\n<div class=\"css-az6x7v\">\n<div class=\"css-1hjaa0k\">\u00a0<\/div>\n<div id=\"inline3__slot\" class=\"css-bkmxmr\" data-adbridg-ad-class=\"inline3\" data-ad=\"true\" data-google-query-id=\"CJaBxuDo7-wCFcoC1QodZYQCyQ\">\n<div id=\"google_ads_iframe_\/4788\/hl\/pagenumber1\/DLB3_0__container__\">\n<div class=\"tlod\">\n<div class=\"tl_ut healthline_Desktop_DLB3_728x90_AB\">\n<div class=\"healthline_Desktop_DLB3_728x90_AB_container healthline_Desktop_DLB3_728x90_AB_flexrules\">\n<div class=\"healthline_Desktop_DLB3_728x90_AB_media_container\">\n<div><a name=\"interactions\"><\/a>Can melatonin interact with other substances?<\/div>\n<p>There are some important things to know about melatonin, its interactions with other substances, and when it\u2019s best to avoid it. Let\u2019s take a closer look.<\/p>\n<h3><span class=\"ez-toc-section\" id=\"What_medications_and_substances_does_melatonin_interact_with\"><\/span>What medications and substances does melatonin interact with?<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>Melatonin may interact with several different types of medications, including:<\/p>\n<ul>\n<li><strong>Blood-thinning medications.<\/strong>\u00a0Taking melatonin with\u00a0blood-thinning medication\u00a0may increase your risk for bleeding.<\/li>\n<li><strong>Epilepsy medications (anticonvulsants).<\/strong>\u00a0Melatonin may make\u00a0these medications\u00a0less effective.<\/li>\n<li><strong>Immunosuppressants.<\/strong>\u00a0Melatonin can potentially interfere with\u00a0immunosuppressive drugs.<\/li>\n<li><strong>Diabetes medications.<\/strong>\u00a0Melatonin use can affect\u00a0blood sugar levels.<\/li>\n<li><strong>Blood pressure medications.<\/strong>\u00a0Blood pressure may get worse when melatonin is taken with\u00a0these medications.<\/li>\n<li><strong>Contraceptive drugs.<\/strong>\u00a0Birth control pills\u00a0may increase the risk of side effects from melatonin.<\/li>\n<\/ul>\n<p>Because melatonin supplements can make you tired and drowsy, avoid mixing them with:<\/p>\n<ul>\n<li>other sleep aids<\/li>\n<li>central nervous system depressants<\/li>\n<li>alcohol<\/li>\n<\/ul>\n<h3><span class=\"ez-toc-section\" id=\"Are_there_any_people_who_should_avoid_taking_melatonin\"><\/span>Are there any people who should avoid taking melatonin?<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>There\u2019s limited research into the safety of using melatonin supplements\u00a0during pregnancy. Also, while melatonin is a normal component of breast milk, there\u2019s little research into the effects of taking melatonin supplements while breastfeeding.<\/p>\n<p>Because of this, it\u2019s best to avoid taking melatonin if you\u2019re:<\/p>\n<ul>\n<li>pregnant<\/li>\n<li>planning to become pregnant<\/li>\n<li>breastfeeding<\/li>\n<\/ul>\n<p>Additionally, it\u2019s important to speak to your doctor before using melatonin if you have:<\/p>\n<ul>\n<li>an\u00a0autoimmune condition<\/li>\n<li>epilepsy<\/li>\n<li>kidney disease<\/li>\n<li>liver disease<\/li>\n<li>had a previous\u00a0allergic reaction\u00a0to melatonin<\/li>\n<\/ul>\n<div><a name=\"when-to-seek-care\"><\/a>When to see your doctor about sleep issues<\/div>\n<p>It\u2019s a good idea to schedule an appointment with your doctor or healthcare provider if you notice that you:<\/p>\n<ul>\n<li>frequently have trouble falling asleep or staying asleep at night<\/li>\n<li>often feel drowsy or tired during the day<\/li>\n<li>have trouble performing your daily activities<\/li>\n<\/ul>\n<p>Your doctor will work with you to discuss your\u00a0sleep routine\u00a0and lifestyle habits. They may also ask you to keep a sleep diary to track the amount of sleep you\u2019re getting over a period of time.<\/p>\n<p>It\u2019s also possible that your doctor will perform a physical exam and order blood tests. These can help them rule out a medical condition that may be causing your sleep issues.<\/p>\n<p>\u00a0<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/aside>\n<\/div>\n<\/div>\n<div class=\"css-0\">\n<h2><span class=\"ez-toc-section\" id=\"i\"><\/span>\u00a0<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":6160,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[335,4214,4215,4213,2621,226],"class_list":["post-6159","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized","tag-body","tag-every","tag-hormone","tag-melatonin","tag-naturally","tag-night"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Is It Safe to Take Melatonin Every Night? - MyMedicPlus<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.mymedicplus.com\/blog\/is-it-safe-to-take-melatonin-every-night\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Is It Safe to Take Melatonin Every Night? - MyMedicPlus\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.mymedicplus.com\/blog\/is-it-safe-to-take-melatonin-every-night\/\" \/>\n<meta property=\"og:site_name\" content=\"MyMedicPlus\" \/>\n<meta property=\"article:published_time\" content=\"2020-11-07T06:42:02+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2022-03-12T09:27:12+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.mymedicplus.com\/blog\/wp-content\/uploads\/2020\/11\/image-1.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1280\" \/>\n\t<meta property=\"og:image:height\" content=\"720\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"mymedicplus\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"mymedicplus\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"6 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.mymedicplus.com\\\/blog\\\/is-it-safe-to-take-melatonin-every-night\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.mymedicplus.com\\\/blog\\\/is-it-safe-to-take-melatonin-every-night\\\/\"},\"author\":{\"name\":\"mymedicplus\",\"@id\":\"https:\\\/\\\/www.mymedicplus.com\\\/blog\\\/#\\\/schema\\\/person\\\/064cee11e5bd38b19d197d3f9491488f\"},\"headline\":\"Is It Safe to Take Melatonin Every Night?\",\"datePublished\":\"2020-11-07T06:42:02+00:00\",\"dateModified\":\"2022-03-12T09:27:12+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.mymedicplus.com\\\/blog\\\/is-it-safe-to-take-melatonin-every-night\\\/\"},\"wordCount\":1285,\"commentCount\":0,\"image\":{\"@id\":\"https:\\\/\\\/www.mymedicplus.com\\\/blog\\\/is-it-safe-to-take-melatonin-every-night\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.mymedicplus.com\\\/blog\\\/wp-content\\\/uploads\\\/2020\\\/11\\\/image-1.jpg\",\"keywords\":[\"Body\",\"Every\",\"hormone\",\"Melatonin\",\"Naturally\",\"night\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/www.mymedicplus.com\\\/blog\\\/is-it-safe-to-take-melatonin-every-night\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.mymedicplus.com\\\/blog\\\/is-it-safe-to-take-melatonin-every-night\\\/\",\"url\":\"https:\\\/\\\/www.mymedicplus.com\\\/blog\\\/is-it-safe-to-take-melatonin-every-night\\\/\",\"name\":\"Is It Safe to Take Melatonin Every Night? 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