Instant HIV test could slow spread of disease

AIDS & HIV

Source: wndu.com

It’s estimated 1.1 million people in the U.S. live with HIV. But one in seven are unaware they even have it. Now, there’s an easier than ever way to find out if a person is HIV-positive.

Rolando Rodriguez can carry a tune. Music and his health are always at the top of his mind. Today he’s taking a screening test for HIV.

“It is an epidemic. I mean, it is something that, that is seriously, could threaten your life and your health,” he said.

The Insti HIV-1/HIV-2 Antibody Test is simple and quick. The process starts with a finger prick. A few drops of blood go into a solution and about 60 seconds later, a patient knows if he’s infected with HIV.

“This is groundbreaking for us,” prevention and sexual health specialist Shirlene Manuel said.

Manuel has been testing for HIV since the 1980s. It used to take weeks to get results. She thinks speeding up the process could slow down the spread of infection.

“It has made a difference in the amount of tests that we see come into the office now and the amount of testing that we are doing out in the community,” she said.

This rapid result test is in line with the President’s Emergency Plan for AIDS Relief to end the epidemic by 2030.

“If we can reach those people that are at high-risk quicker, we can get that epidemic really down where it should be,” Brian Bailey said.

Rodriguez’s test came back negative, giving him peace of mind and something to sing about.

Experts say there is one thing for patients to consider: Very recent HIV infection might not be picked up by the Insti test since the body might not have produced enough detectable antibodies. Doctors suggest patients ask their health care providers if they should consider getting retested in three to six months.

BACKGROUND: Acquired Immunodeficiency Syndrome, also known as AIDS, can be caused by HIV Type 1 and HIV Type 2. HIV is transmitted mainly by sexual contact, exposure to blood or blood affected products or from an infected mother to her fetus. Antibodies specific for HIV envelope proteins are prevalent in blood or blood products from people at high risk of contracting AIDS as well as people with AIDS. When HIV leaves a host cell, it takes part of that cell’s plasma membrane and becomes an HIV envelope. The HIV envelope isn’t only made up of components from the host. It is also made up of HIV envelope proteins. HIV envelope proteins include gp41, gp120, and gp160. GP stands for “glycoprotein”. Glycoproteins have carbohydrate, or sugar, components as well as a protein backbone. The number after the gp refers to the proteins’ length. HIV interferes with the body’s ability to fight infection and disease by damaging the immune system. The U.S. Centers for Disease Control and Prevention estimates that up to 25% of people living with HIV in the United States are unaware of their infection and thus don’t benefit from antiretroviral therapy. 

SYMPTOMS AND DIAGNOSING: According to Shirlene Manuel, MD, Metro Inclusive Health in Tampa, FL, back in 1988, it could take anywhere from two to six weeks to get results back. More recently, HIV testing would take at least 20 minutes before results were given. This has caused many individuals to avoid getting tested due to the fear of their results. There are four stages to the progression from HIV to AIDS. The first is Acute HIV, this then becomes Chronic HIV, then Symptomatic HIV Infection and finally the progression to AIDS. Due to the introduction of antiviral treatments, most people with HIV in the U.S. don’t develop AIDS. Although leaving it untreated, HIV can turn into AIDS in about 8 to 10 years. There are a few treatment options to prevent the spread of HIV. If an individual believes they have been exposed to HIV through sex, needles or in the workplace, they should contact a doctor as soon as possible. Patients can also take post-exposure prophylaxis (PEP) as soon as possible. If taken in the first 72 hours, it can greatly reduce the risk of becoming infected with HIV. Other prevention tactics include: wearing a new condom every time you have sex, using a clean needle, tell your partners if you’re HIV positive and if pregnant a patient should seek medical care right away. There is no cure for HIV/AIDS as of now, but medications can dramatically slow the progression of the disease. 

INSTI TESTING: A new test is being introduced as a quicker solution to getting results on HIV testing. The INSTI test is where physicians take a drop of blood, put it in a solution and in a minute, results are presented. It is a rapid in vitro qualitative test for the detection of antibodies. It also detects HIV Type 1 and HIV Type 2 in blood, fingerstick blood, serum or plasma. Over 15 million tests have already been performed.