Dr. Sarah Nguyen

Dr. Sarah Nguyen is a consultant neurologist at Prince of Wales Hospital in Sydney, where she is Head of the Neuroimmunology and Multiple Sclerosis Clinic. With over 18 years of experience in clinical neurology, Dr. Nguyen is widely regarded as one of Australia's leading authorities on multiple sclerosis, autoimmune neurological disorders, and stroke medicine.

Dr. Nguyen completed her medical training at the University of New South Wales and undertook her neurology fellowship at Prince of Wales Hospital, one of Australia's busiest tertiary neurology centres. She subsequently completed a PhD in neuroimmunology and a postdoctoral fellowship at the University of California, San Francisco (UCSF), focusing on B-cell biology in multiple sclerosis.

In addition to her clinical work, Dr. Nguyen is an Associate Professor in the UNSW Faculty of Medicine, teaching medical students and supervising postgraduate neurology trainees. She consults privately at Sydney Neurological Institute, providing specialist neurological assessments for patients throughout New South Wales and beyond.

Dr. Nguyen completed her MBBS at the University of New South Wales (UNSW), followed by basic physician training at Prince of Wales Hospital. She completed advanced training in neurology with the Royal Australasian College of Physicians (RACP), obtaining her FRACP Fellowship.

Her PhD in Neuroimmunology, completed at UNSW, focused on T-regulatory cell dysfunction in multiple sclerosis. She subsequently undertook a two-year postdoctoral fellowship at UCSF's Weill Institute for Neurosciences, one of the world's leading centres for MS research. She has completed additional specialist training in stroke medicine and holds additional fellowship with the Australasian Faculty of Rehabilitation Medicine (FAFRM).

Dr. Nguyen's primary clinical focus is multiple sclerosis and neuroimmunological conditions. She has extensive experience initiating and monitoring high-efficacy disease-modifying therapies (DMTs) for MS, including natalizumab, ocrelizumab, and alemtuzumab. She leads a dedicated MS clinic at Prince of Wales Hospital, managing over 400 active MS patients.

In stroke medicine, Dr. Nguyen participates in the acute stroke response team, administering IV thrombolysis and coordinating mechanical thrombectomy for eligible patients. She also has expertise in epilepsy management, performing EEG interpretation and initiating antiepileptic therapy. Botulinum toxin (Botox) injections for spasticity, chronic migraine, and movement disorders form part of her procedural repertoire.

Dr. Nguyen has published over 75 peer-reviewed articles in journals including Neurology, The Lancet Neurology, Brain, and Multiple Sclerosis Journal. Her research spans neuroimmunological mechanisms in MS, biomarker development for disease progression prediction, and clinical trial outcomes for high-efficacy MS therapies.

She has received research grants from the National Health and Medical Research Council (NHMRC) and MS Research Australia, and is currently chief investigator on two NHMRC-funded projects investigating serum neurofilament light chain (NfL) as a biomarker for treatment response in MS. She is a member of the International MS Genetics Consortium and the MS-STAT2 trial steering committee.

Dr. Nguyen sees patients from across the Asia-Pacific region seeking expert neurological assessment in Australia. Her bilingual ability in English and Vietnamese is particularly valued by Vietnamese-Australian patients and those from Vietnam seeking specialist care.

Prince of Wales Hospital has well-established international patient pathways, and Dr. Nguyen's team can coordinate remote pre-consultation MRI review, video consultation appointments, and expedited clinic scheduling for international visitors. She works closely with neurologists in New Zealand, Fiji, and across Southeast Asia who refer complex neuroimmunological cases to her practice.

Dr. Nguyen has received the ANZAN Distinguished Service Award, the MS Research Australia Postdoctoral Research Fellowship, and the UNSW Vice-Chancellor's Excellence in Teaching Award. She was named in the Medical Observer Neurology Excellence list and has received competitive funding exceeding AUD 4.5 million from national research bodies. She is a sought-after speaker at national and international neurology conferences.