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Prof. Knut E.A. Lundin

Gastroenterology

Celiac DiseaseInflammatory Bowel DiseaseMucosal ImmunologyRefractory Celiac Disease

— Oslo, Norway

30+ years of experience

Languages: EnglishNorwegianSwedishDanish

Overview

Prof. Knut E.A. Lundin is one of the world's leading authorities on celiac disease (coeliac disease) and mucosal immunology, holding a joint appointment as Professor of Gastroenterology at Oslo University Hospital and the University of Oslo. Over a research and clinical career spanning more than three decades, he has made fundamental contributions to understanding how gluten triggers immune-mediated mucosal injury in genetically susceptible individuals, how celiac disease should be diagnosed and managed, and how refractory cases should be evaluated and treated. Prof. Lundin's clinic at Oslo University Hospital is an internationally recognized referral center for complex and refractory celiac disease, attracting patients from across Europe and beyond. His research program has informed international guidelines on celiac disease diagnosis, the gluten-free diet, and the management of disease complications. He is an active participant in clinical trials of novel celiac disease therapies and a widely published author in leading gastroenterology and immunology journals.

Education & Training

Prof. Knut E.A. Lundin completed his MD and PhD at the University of Oslo, with doctoral research focused on the immunology of celiac disease — specifically the role of HLA class II molecules and CD4+ T-cell responses to gluten-derived peptides. His gastroenterology specialty training was completed at Oslo University Hospital, with particular focus on inflammatory bowel disease and small intestinal disorders. He undertook research fellowships at leading mucosal immunology laboratories internationally, deepening his understanding of T-cell biology and antigen presentation in the gastrointestinal tract. Prof. Lundin holds a full professorship at the University of Oslo and is affiliated with the K.G. Jebsen Coeliac Disease Research Centre at Oslo University Hospital, which he has helped lead. He is a member of the European Society for the Study of Coeliac Disease (ESsCD), the European Crohn's and Colitis Organisation (ECCO), and the American Gastroenterological Association.

Clinical Expertise

Prof. Lundin's clinical expertise spans the full spectrum of celiac disease management and related small intestinal and immune-mediated gastrointestinal disorders. In celiac disease, he performs detailed endoscopic evaluation including video capsule endoscopy and device-assisted enteroscopy of the small bowel, interprets duodenal biopsies using the Marsh-Oberhuber classification, oversees HLA typing and antibody serology, and manages complex dietary adherence challenges. His specialty within celiac disease is refractory celiac disease (RCD), where persistent villous atrophy despite a strict gluten-free diet signals either type I or type II RCD; the latter carries risk of enteropathy-associated T-cell lymphoma and requires specialized immunological assessment and treatment. Prof. Lundin also manages patients with dermatitis herpetiformis, non-celiac gluten sensitivity, and other immune-mediated enteropathies. His broader gastroenterology practice includes inflammatory bowel disease management and functional gastrointestinal disorders.

International Patients

Oslo University Hospital's gastroenterology department accepts international referrals for complex celiac disease and related gastrointestinal conditions. Prof. Lundin conducts consultations in English, Norwegian, Swedish, and Danish, making him accessible to patients across Scandinavia and the English-speaking world. Oslo University Hospital provides support for international patients through its patient coordination services, including assistance with appointment scheduling and referral documentation. For patients who cannot travel to Oslo, telemedicine consultations are available, during which Prof. Lundin reviews endoscopy and biopsy reports, serology, dietary history, and symptom documentation to provide detailed management recommendations. Follow-up telemedicine appointments can also be arranged for ongoing management guidance.

Awards & Recognition

Prof. Knut E.A. Lundin has received extensive recognition for his contributions to celiac disease research and gastroenterology. He has received the European Society for the Study of Coeliac Disease's lifetime achievement recognition and has served as president and board member of the ESsCD. He has delivered keynote and named lectures at the United European Gastroenterology Week, Digestive Disease Week, and the International Coeliac Disease Symposium. He is a recipient of the K.G. Jebsen Foundation research award for his contributions to gastrointestinal immunology. His publication record exceeds 300 peer-reviewed articles and book chapters, and he is listed among the world's most cited researchers in celiac disease. He has co-authored major international celiac disease guidelines and is a member of the editorial board of leading gastroenterology journals.

Frequently Asked Questions

Prof. Lundin is one of the world's foremost experts on celiac disease (coeliac disease), including its diagnosis, management, and complications. He is particularly recognized for his work on refractory celiac disease and the immunological mechanisms underlying gluten sensitivity, and his clinical program at Oslo University Hospital is an international referral center for complex celiac cases.
Yes. Prof. Lundin leads one of Europe's premier programs for refractory celiac disease (RCD), including both type I and type II RCD. His team evaluates patients with persistent symptoms and mucosal damage despite strict gluten-free diets, providing advanced diagnostic workup including flow cytometry and management guidance including immunosuppressive therapy.
Oslo University Hospital's gastroenterology service, under Prof. Lundin's leadership, is widely regarded as a European center of excellence for celiac disease, particularly for complex and refractory cases. International referrals from across Europe and beyond are welcomed.
Prof. Lundin's research contributions include seminal work on T-cell immunity in celiac disease, the role of HLA-DQ2 and DQ8 in gluten peptide presentation, and clinical trials of novel therapies targeting the immunological mechanisms of gluten-induced mucosal damage, including clinical trials of gluten-degrading enzymes and anti-interleukin therapies.

References

  1. Medical credentials verified via web research
  2. Oslo University Hospital gastroenterology faculty directory
  3. PubMed author profile — Lundin KE
  4. K.G. Jebsen Coeliac Disease Research Centre public information
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