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Scar Revision — Cost, Top Hospitals & Success Rates | MyMedicPlus

Updated: 2026-06-26
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Quick Facts

Specialties Involved
Plastic Surgery, Dermatology, Burns Surgery
Scar Maturation Period
12–18 months before definitive revision
Treatment Types
Surgical, Laser, Injectable, Topical, Combination
Sessions Required
1–6 depending on technique and scar type
Downtime
Varies: none (topical) to 2–6 weeks (surgical excision)
Keloid Recurrence Risk
50–80% after excision alone; lower with adjuvant therapy
Reviewed By
MyMedicPlus Medical Review Board
Last Reviewed
2026-06-26

Understanding Scar Formation and the Goals of Scar Revision

<p>A scar is the inevitable biological result of wound healing. When the skin and deeper tissues are disrupted by trauma, surgery, burns, or infection, the body repairs the breach through a complex cascade of coagulation, inflammation, proliferation, and tissue remodelling. The resultant scar tissue is composed primarily of type I collagen — mechanically strong but architecturally disorganised compared to the basket-weave collagen pattern of normal skin. This disorganisation, combined with the absence of normal skin appendages (hair follicles, sweat glands, and sebaceous glands), gives scar tissue its characteristic visual and tactile properties: a flat or raised, pale or pigmented, smooth and often shiny appearance that differs clearly from surrounding skin.</p><p>Scar revision encompasses the full spectrum of medical and surgical interventions designed to improve the appearance, texture, function, or symptoms of an existing scar. The goal is not the elimination of the scar — no current treatment can restore the skin to its pre-injury state, and patients should understand this clearly — but rather its optimisation. A well-revised scar may be less visible, less symptomatic, functionally less restrictive, and psychologically less burdensome than the original scar.</p><p>The type of scar revision most likely to succeed depends entirely on the type of scar, its anatomical location, the patient's age and skin type, the time elapsed since the original injury, and the patient's expectations and psychological relationship with the scar. A keloid on the earlobe requires a fundamentally different approach from a depressed acne scar on the cheek or a burn contracture across the axilla.</p><p>Scar revision is both an art and a science. Plastic surgeons, dermatologists, and burns surgeons each bring complementary skills to this field. The most effective outcomes typically result from a combination of modalities — for example, surgical excision followed by intralesional corticosteroid injections and laser resurfacing — rather than any single intervention. A thorough pre-treatment assessment and a realistic, patient-centred treatment plan are the foundations of successful scar management.</p>

Types of Scars Amenable to Revision

<p>Different scar types have distinct pathophysiology, clinical features, and optimal management strategies. Accurate classification is essential for selecting the appropriate revision approach.</p><h3>Hypertrophic Scars</h3><p>Hypertrophic scars are raised, erythematous, and often pruritic scars that remain within the boundaries of the original wound. They result from dysregulation of the normal proliferative phase of wound healing, with excessive collagen deposition relative to degradation. They are particularly common after burns and across high-tension anatomical sites (sternum, shoulder, knee). Unlike keloids, hypertrophic scars typically regress spontaneously over 12–18 months and respond well to conservative treatments such as silicone gel sheeting and compression therapy.</p><h3>Keloid Scars</h3><p>Keloids are pathological fibroproliferative tumours that extend well beyond the margins of the original wound, invading surrounding normal skin. They do not regress spontaneously, frequently recur after excision, are often tender and pruritic, and can cause significant functional impairment. They occur disproportionately in people with darker skin phototypes (Fitzpatrick types IV–VI) and have a strong genetic predisposition. Common sites include the earlobes (after piercing), sternum, deltoid region, and mandibular line. Keloid management requires multimodal therapy: surgery alone carries recurrence rates of 50–80%, but surgery combined with adjuvant post-operative corticosteroid injections, radiotherapy, or pressure therapy achieves substantially better long-term outcomes.</p><h3>Atrophic and Depressed Scars</h3><p>Atrophic scars result from insufficient collagen deposition during healing, producing a depression or pit below the level of surrounding skin. They are extremely common sequelae of acne vulgaris (acne scars) and chickenpox. Morphologically, acne scars are classified as ice-pick (deep, narrow), boxcar (broad, angular), or rolling (broad, undulating) — each responding differently to specific treatments including fractional laser resurfacing, subcision, punch excision, and dermal fillers.</p><h3>Contracture Scars (Burn Scars)</h3><p>Burn scars — particularly those involving flexion creases such as the neck, axilla, antecubital fossa, palm, and digital web spaces — commonly develop scar contracture, in which the maturing scar tissue shortens progressively, limiting joint range of motion. Severe contractures can restrict eating, breathing, dressing, and self-care, and require surgical release and reconstruction as a functional matter rather than purely cosmetic.</p><h3>Wide, Stretched, or Unfavourably Oriented Surgical Scars</h3><p>Surgical scars placed against the direction of Langer skin tension lines (relaxed skin tension lines), under excessive tension, or poorly closed may heal widened, spread, and conspicuous. These technically normal scars — without pathological fibroproliferation — can be significantly improved by surgical re-excision with meticulous technique and orientation.</p>

Eligibility for Scar Revision: Who Is a Candidate?

<p>Patient selection for scar revision involves assessment of scar characteristics, patient expectations, skin type, general health, and the time elapsed since the original injury. Not all scars are suitable for revision, and not all patients will achieve the outcomes they expect.</p><h3>Scar Maturity — Timing Is Critical</h3><p>The most important prerequisite for surgical scar revision is scar maturity. Wound healing and scar remodelling continue for 12–24 months after injury; a scar that appears prominent and red at 3 months may be virtually imperceptible at 18 months. Operating on an immature scar risks recreating the same problem. Most plastic surgeons recommend waiting a minimum of 12–18 months after the original wound before definitive surgical scar revision, unless the indication is functional (e.g., contracture causing joint restriction) or the scar is clearly abnormal from an early stage (e.g., a rapidly expanding keloid).</p><h3>Skin Type and Keloid Risk</h3><p>Skin phototype (Fitzpatrick classification) is a critical eligibility factor. Patients with darker skin types (IV–VI) have a substantially higher risk of post-inflammatory hyperpigmentation after ablative laser treatments, and of keloid formation after surgical scar excision. For these patients, aggressive laser or surgical approaches must be undertaken with greater caution, and adjuvant anti-scarring therapy is more important.</p><h3>Realistic Patient Expectations</h3><p>One of the most important eligibility criteria for scar revision is that the patient holds realistic expectations. A scar cannot be completely erased — the goal is improvement, not perfection. Patients who expect a return to pre-injury skin appearance will inevitably be disappointed. A frank pre-operative discussion about realistic outcomes, illustrated with photographic examples of typical results, is essential. Patients with body dysmorphic disorder (BDD) — a psychiatric condition characterised by excessive preoccupation with perceived physical flaws — are generally not suitable for scar revision and should be referred for psychological assessment.</p><h3>Absence of Active Infection or Inflammation</h3><p>Scar revision should not be performed through active infected or inflamed tissue. Any wound infection must be fully treated before revision surgery is considered.</p><h3>Systemic Health Factors</h3><p>Uncontrolled diabetes impairs wound healing and increases infection risk; glycaemic control should be optimised before surgery. Patients taking anticoagulants, corticosteroids, or immunosuppressants require specific perioperative management. Smokers should be advised to stop smoking at least 6 weeks before any surgical scar revision, as smoking dramatically impairs wound perfusion and healing.</p>

Scar Revision Techniques: Surgical and Non-Surgical Options

<p>Modern scar management employs a broad armamentarium of interventions, often used in combination to maximise outcomes. The optimal approach is determined by scar type, location, patient skin type, and available resources.</p><h3>Surgical Excision with Primary Closure</h3><p>The most straightforward surgical approach: the scar is excised entirely and the wound re-closed with meticulous tension-free layered suturing, placing the final scar within a skin tension line or anatomical subunit boundary to maximise camouflage. This is most effective for wide or poorly positioned surgical scars on low-tension anatomical sites. It will not prevent keloid recurrence without adjuvant therapy.</p><h3>Geometric Closure Techniques: Z-Plasty and W-Plasty</h3><p>Z-plasty is the most widely used geometric scar revision technique. Two triangular skin flaps are transposed to reorient the long axis of the scar, break up its linearity, and redistribute tension. Standard Z-plasty achieves a 75% lengthening of the central limb — invaluable for releasing linear contractures. Multiple Z-plasties in series are used for long contractures. W-plasty converts a linear scar into a continuous irregular geometric pattern that is less conspicuous to the eye, which naturally tracks straight edges more readily than broken or geometric outlines.</p><h3>Skin Grafts and Local or Regional Flaps</h3><p>For large contractures or complex scarred areas where primary closure is not possible, skin grafts (split-thickness or full-thickness) or local/regional flaps are used to replace the excised scar with healthier, more pliable skin. Flap reconstruction provides superior colour, texture, and durability compared to skin grafting but is technically more demanding.</p><h3>Intralesional Corticosteroid Injections</h3><p>Intralesional triamcinolone acetonide (10–40 mg/mL) injected directly into the scar suppresses fibroblast proliferation, reduces collagen synthesis, and induces collagen degradation. It is first-line treatment for hypertrophic scars and an essential adjuvant after keloid excision. Treatments are given at 4–8 week intervals; 3–6 sessions are typically required. Side effects include skin atrophy, telangiectasia, and hypopigmentation at the injection site.</p><h3>Fractional Laser Resurfacing</h3><p>Ablative (CO2 or Er:YAG) and non-ablative (Fraxel 1550 nm) fractional lasers create precise columns of thermal injury in the skin, stimulating collagen remodelling, improving scar texture, reducing erythema, and treating atrophic acne scars. Fractional laser is particularly effective for atrophic, acne-type, and post-surgical scars. Vascular-targeting lasers (pulsed dye laser, 585–595 nm) specifically target haemoglobin in erythematous or vascular hypertrophic scars, reducing redness and improving texture.</p><h3>Silicone Gel Sheeting and Topical Silicone</h3><p>Silicone gel sheeting, worn for 12–24 hours per day for 3–6 months, is the best-evidenced non-invasive treatment for preventing and improving hypertrophic scars. The mechanism involves occlusion, hydration of the stratum corneum, and direct silicone effects on fibroblasts. Topical silicone gels provide equivalent benefit with better compliance. These are first-line for immature hypertrophic scars.</p><h3>Post-Operative Radiotherapy for Keloids</h3><p>Low-dose radiotherapy administered within 24–48 hours of keloid excision (typically 15–20 Gy in 3–5 fractions) suppresses fibroblast proliferation at the excision site, dramatically reducing recurrence rates to 10–30% compared to 50–80% after excision alone. The radiation dose used is too low to cause systemic effects but should not be applied near reproductive organs, the thyroid, or the eyes.</p>

Benefits of Scar Revision

<p>Scar revision, when correctly indicated and performed by experienced practitioners, delivers a range of meaningful functional, cosmetic, and psychological benefits.</p><h3>Functional Improvement in Contracture Scars</h3><p>For burn contractures limiting joint mobility — particularly across the axilla, elbow, wrist, hand, neck, or knee — scar revision through Z-plasty, flap reconstruction, or skin grafting can dramatically restore range of motion. Patients who previously could not raise their arm above shoulder height, close their hand into a fist, or turn their head may recover functional independence that transforms their daily life. Functional scar revision is sometimes covered by health insurance even when purely cosmetic revision is not.</p><h3>Reduction in Scar Symptoms</h3><p>Hypertrophic scars and keloids are frequently pruritic (itchy), painful, and hypersensitive to touch — symptoms that persist for months to years and can be profoundly disruptive to sleep, clothing tolerance, and daily activity. Intralesional corticosteroid injections, silicone sheeting, and laser treatment reliably reduce scar-related itch, pain, and dysaesthesia in a majority of patients, often within a few treatment sessions.</p><h3>Improved Cosmetic Appearance</h3><p>Visible scars — particularly those on the face, neck, or hands — can cause significant social self-consciousness and avoidance of social situations. Evidence-based scar revision techniques can meaningfully reduce scar visibility: flattening hypertrophic or keloid scars, improving the texture and colour of burn scars, raising depressed acne scars to the level of surrounding skin, and reorienting prominent linear surgical scars into less conspicuous anatomical positions.</p><h3>Psychological and Quality-of-Life Benefits</h3><p>Multiple published studies document significant improvements in quality of life, self-esteem, social functioning, and anxiety after successful scar revision in patients with burns, trauma, or disfiguring acne scars. The psychological burden of visible scarring — particularly facial scarring — is well-recognised, and scar revision is increasingly acknowledged as an important component of holistic rehabilitation after traumatic injury or burns.</p><h3>Prevention of Scar Progression</h3><p>Early intervention — particularly silicone sheeting, compression therapy, and prophylactic intralesional corticosteroid injections — can arrest the progression of hypertrophic scarring and prevent established keloid formation in high-risk individuals or at high-risk wound sites, reducing the need for more invasive revision later.</p>

Risks and Potential Complications of Scar Revision

<p>While scar revision is generally safe, all interventions carry risks that patients must understand and accept before proceeding. The risk profile varies substantially by technique.</p><h3>Scar Recurrence or Worsening</h3><p>The most significant risk of any scar revision is that the resulting scar is no better than — or is worse than — the original. This risk is highest for keloid excision without adjuvant therapy and for scar revision performed on the ears, sternum, deltoid, and jawline in high-risk individuals. Patients with a prior history of keloid formation should be counselled that any surgical intervention may stimulate new keloid growth.</p><h3>Infection and Wound Dehiscence</h3><p>Post-operative wound infection and premature wound opening (dehiscence) impair healing and can produce a worse scar than the original. Risk is increased in smokers, diabetics, immunocompromised patients, and when wounds are placed under excessive tension. Prophylactic antibiotics are used at surgeon discretion; careful perioperative skin preparation and sterile technique are essential.</p><h3>Pigmentation Changes</h3><p>Both hyperpigmentation (darkening) and hypopigmentation (lightening) of the skin can occur after ablative laser treatment, dermabrasion, or chemical peels. Hyperpigmentation is particularly common in darker skin types (Fitzpatrick IV–VI) and can be more aesthetically distressing than the original scar. Using gentler laser parameters, treating off-season (avoiding sun exposure around treatment), and applying rigorous sun protection and topical hydroquinone prophylactically minimise this risk.</p><h3>Skin Atrophy and Telangiectasia from Corticosteroid Injections</h3><p>Over-injection of intralesional triamcinolone can produce skin atrophy (thinning and depression of the surrounding normal skin) and telangiectasia (prominent small blood vessels) at the injection site, which can be as aesthetically undesirable as the original scar. These effects are partially reversible over time but may require treatment with vascular laser.</p><h3>Haematoma and Seroma</h3><p>Accumulation of blood (haematoma) or serous fluid (seroma) beneath a surgically revised scar can impair wound healing, increase infection risk, and produce a wider, potentially keloid-prone scar. Careful intraoperative haemostasis and judicious use of drains minimise these risks.</p><h3>Anaesthetic Risks</h3><p>Most scar revision procedures are performed under local anaesthesia, making general anaesthetic risks relevant only for more extensive reconstructive procedures. Lignocaine allergy, though uncommon, is a recognised risk of local anaesthetic use. Topical anaesthetic agents (EMLA cream) used before laser treatment carry a small risk of methaemoglobinaemia when applied over large surface areas — a point particularly relevant in paediatric patients.</p>

Post-Treatment Care and Recovery

<p>The post-treatment care plan is as important as the treatment itself in determining the final outcome of scar revision. Non-compliance with post-treatment recommendations is one of the most common reasons for suboptimal results.</p><h3>Immediate Wound Care After Surgical Revision</h3><p>Surgical wounds require daily cleaning with saline or dilute antiseptic solution, followed by application of a non-adherent dressing and, if appropriate, topical antibiotic ointment during the epithelialisation phase. Sutures are removed at 5–7 days for facial wounds and 10–14 days for body wounds. Tension-reducing wound support strips (Steri-Strips) can be applied after suture removal and continued for 2–4 weeks.</p><h3>Silicone Therapy — Long-Term Commitment</h3><p>Silicone gel sheeting or topical silicone gel should be applied to the healed wound from the day of suture removal (once the epithelial surface is intact) and continued for a minimum of 3–6 months. Compliance for 12–24 hours per day is necessary for efficacy. This is the most important single measure for preventing hypertrophic scar formation and should be emphasised clearly to every patient.</p><h3>Sun Protection</h3><p>Immature scars are extremely vulnerable to UV-induced post-inflammatory hyperpigmentation, which can darken and discolour the scar permanently. Patients must apply SPF50+ broad-spectrum sunscreen to any exposed scar for a minimum of 12 months and ideally longer. Physical sun protection (clothing, hats) is preferable for areas that are difficult to cover with sunscreen.</p><h3>Post-Laser Recovery</h3><p>After ablative fractional laser treatment the skin is typically red, swollen, and moist for 3–7 days. A gentle emollient (petroleum jelly or equivalent) should be applied continuously during the healing phase. Patients should avoid social exposure during this period and must not pick or abrade the healing skin. Non-ablative fractional laser causes minimal downtime but may produce 24–72 hours of erythema and swelling.</p><h3>Compression Therapy for Burns Scars</h3><p>Custom-fitted compression garments delivering 25–40 mmHg of continuous pressure are the standard of care for burn scar management. They must be worn 23 hours per day for 12–24 months to be effective. Compression reduces scar vascularity, flattens raised scars, and reduces keloid and hypertrophic scar formation. Compliance is challenging but critically important.</p><h3>Follow-Up Schedule</h3><p>After surgical scar revision: review at 1 week (suture removal), 6 weeks, 3 months, and 12 months. After laser treatment: review at 4–8 weekly intervals for further treatment sessions; total 3–6 sessions required for most conditions. After corticosteroid injections: review at 4–8 week intervals for further injections as needed, monitoring for atrophy.</p>

Cost Factors and International Pricing

<p>Scar revision encompasses a wide range of techniques with markedly different costs. The total investment depends on the treatment modality, the number of sessions required, the anatomical site, the treating specialty and setting, and whether the indication is functional (more likely to be insured) or purely cosmetic (usually self-funded).</p><h3>Non-Surgical Treatments — Most Affordable Entry Point</h3><p>Silicone gel sheets (USD 20–80 per sheet, reusable for 3–6 months) are the most cost-effective evidence-based treatment for hypertrophic scars. Topical silicone gels cost USD 30–80 per tube, lasting 4–6 weeks. Compression garments range from USD 100–500 per garment depending on body area and degree of customisation. These costs are manageable for most patients and represent excellent value given the clinical evidence.</p><h3>Intralesional Corticosteroid Injections</h3><p>Corticosteroid injection sessions typically cost USD 100–400 per session (US private practice), with 3–6 sessions needed. Some dermatologists include this in a comprehensive scar management package. Corticosteroid injection for keloids is frequently included in medically necessary treatment covered by health insurance in many countries.</p><h3>Laser Treatment Costs</h3><p>A single fractional laser session costs USD 500–2,500 depending on the laser platform, the surface area treated, and the geographic market. Typically 3–6 sessions are needed for acne scar revision, totalling USD 1,500–10,000. Pulsed dye laser for erythematous hypertrophic scars costs USD 300–1,200 per session. In medical tourism destinations such as Thailand, South Korea, and India, equivalent laser treatments are available at 40–70% lower cost.</p><h3>Surgical Scar Revision</h3><p>Surgical scar revision (excision with primary closure, Z-plasty, or flap reconstruction) under local anaesthesia in an outpatient setting typically costs USD 1,500–6,000 in the United States. Procedures requiring general anaesthesia in a hospital or ambulatory surgery centre add facility and anaesthesia fees, increasing total costs to USD 5,000–20,000 for complex reconstruction. Insurance coverage for functional burn contracture surgery is generally available; purely cosmetic revision is typically self-funded.</p><h3>Radiotherapy Adjuvant for Keloids</h3><p>Post-excision radiotherapy for keloids — highly effective but often underutilised — adds USD 2,000–8,000 per course in the United States, though it may be covered by insurance as an adjuvant to medically necessary keloid surgery. In public health systems, this cost is borne by the health service.</p>

Non-Revision Alternatives and Complementary Approaches

<p>Not all scars require active revision. Many scars improve substantially with time alone, or with simple non-invasive measures that are worthwhile before committing to more intensive interventions.</p><h3>Watchful Waiting — The Value of Patience</h3><p>Scar maturation takes 12–24 months. During this period, even prominent, red, raised scars typically soften, flatten, and fade substantially. Patients and clinicians who allow adequate scar maturation before revision surgery often find that the scar no longer warrants intervention. The universal recommendation to wait a minimum of 12–18 months before surgical revision reflects this reality. Early patient anxiety and impatience to "do something" must be managed with reassurance, education, and the initiation of conservative measures such as silicone sheeting during the waiting period.</p><h3>Topical Treatments</h3><p>Topical onion extract gel (e.g., Mederma, Contractubex) is widely used for scar management; evidence for efficacy beyond moisturising effects is limited but it is safe and affordable. Vitamin E is popularly applied to scars despite limited clinical evidence of benefit and reports of contact dermatitis in some patients. Tretinoin (topical retinoid) may improve texture and pigmentation in some scar types. SPF50+ sunscreen is non-negotiable for all visible scars during the maturation period.</p><h3>Camouflage Cosmetics</h3><p>Medical-grade concealer products and colour-corrective cosmetics (available from brands such as Dermablend and KVD) can effectively conceal facial scars, dyspigmentation, and vitiligo patches with a natural-looking finish that withstands normal daily activity. Paramedical tattooing (medical micropigmentation) can camouflage depigmented burn scars and areolar reconstruction scars with impressive naturalistic results.</p><h3>Physiotherapy and Scar Massage</h3><p>Manual scar massage with a neutral emollient, applied for 5–10 minutes twice daily, improves scar suppleness, reduces scar tethering to underlying tissues, and can meaningfully improve functional range of motion in contracture scars. Physiotherapy-led scar massage programmes are a standard component of burns rehabilitation and are supported by evidence, particularly in the early maturation phase.</p><h3>Dermal Fillers for Atrophic Scars</h3><p>For atrophic acne scars or depressed traumatic scars, injectable dermal fillers (hyaluronic acid, calcium hydroxylapatite, or poly-L-lactic acid) can temporarily raise the depressed scar to the level of surrounding skin, achieving a smoother appearance without surgery. Results are temporary (6–18 months) and require repeat treatment, but they are non-surgical and carry minimal downtime.</p>

Frequently Asked Questions

No — scar revision cannot completely remove a scar or restore the skin to its original appearance. The goal of scar revision is improvement: making the scar less visible, less symptomatic, flatter, better camouflaged within skin tension lines, or functionally less restrictive. A realistic expectation is that a well-revised scar will be significantly less noticeable than the original, but some trace of the scar will always remain. Patients should have a frank discussion with their surgeon about likely outcomes before committing to treatment.
Most plastic surgeons recommend waiting 12–18 months after the original injury or surgery before considering surgical scar revision, to allow the scar to fully mature. During maturation, even prominent, raised, red scars typically soften, flatten, and fade significantly. Conservative measures — silicone sheeting, sun protection, massage — should be started early and continued during this waiting period. Functional scar revision (e.g., for contractures limiting joint movement) may be undertaken earlier when there is a clear functional benefit that cannot wait for full scar maturation.
Both hypertrophic scars and keloids are raised, often reddish scars resulting from excessive collagen deposition during healing, but they are distinct entities. A hypertrophic scar remains within the boundaries of the original wound and often improves spontaneously over 12–18 months. A keloid, by contrast, grows beyond the original wound margin into surrounding normal skin, does not spontaneously regress, is often tender or itchy, and has a high rate of recurrence after treatment. Keloids are more common in people with darker skin types and require more aggressive, multimodal treatment than hypertrophic scars.
The number of laser sessions required for acne scar revision varies with scar type, depth, skin tone, and laser platform used. Most patients require 3–6 sessions of fractional laser resurfacing spaced 4–8 weeks apart, after which significant improvement in scar texture and depth is achieved. Deeper ice-pick scars may require additional preparatory treatment (such as punch excision or TCA CROSS technique) before laser treatment. Maintenance sessions may be needed at 12–24 month intervals. A realistic improvement in scar appearance of 40–70% can be expected after a complete treatment series.
Coverage depends on the clinical indication and the insurer. Scar revision for purely cosmetic reasons (improving the appearance of a mature, stable scar without functional impairment) is generally not covered by health insurance. However, scar revision for functional indications — such as releasing a burn contracture that limits joint movement, correcting a scar causing ectropion of the eyelid, or treating a symptomatic keloid — is frequently covered, at least in part. Patients should obtain written pre-authorisation from their insurer, supported by a letter from their surgeon documenting the functional impairment and clinical necessity of the procedure.

References

  1. Mustoe TA et al. International clinical recommendations on scar management. Plast Reconstr Surg. 2002;110(2):560–571.
  2. Gauglitz GG et al. Hypertrophic scarring and keloids: pathomechanisms and current and emerging treatment strategies. Mol Med. 2011;17(1-2):113–125.
  3. Gold MH et al. Updated International Clinical Recommendations on Scar Management: Part 2—Algorithms for Scar Prevention and Treatment. Dermatol Surg. 2014;40(8):825–831.
  4. van Leeuwen MCE et al. Postoperative low-dose-rate brachytherapy in the treatment of keloids. Int J Radiat Oncol Biol Phys. 2015;92(5):1107–1113.
  5. Ogawa R. Keloid and hypertrophic scars are the result of chronic inflammation in the reticular dermis. Int J Mol Sci. 2017;18(3):606.
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